Articles | Volume 8, issue 1
https://doi.org/10.5194/amt-8-471-2015
https://doi.org/10.5194/amt-8-471-2015
Research article
 | 
29 Jan 2015
Research article |  | 29 Jan 2015

A semi-automated system for quantifying the oxidative potential of ambient particles in aqueous extracts using the dithiothreitol (DTT) assay: results from the Southeastern Center for Air Pollution and Epidemiology (SCAPE)

T. Fang, V. Verma, H. Guo, L. E. King, E. S. Edgerton, and R. J. Weber

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Short summary
This work summarizes a newly developed semi-automated system for quantifying the oxidative potential of aerosol aqueous extracts using the dithiothreitol (DTT) assay. 500 sample analyses indicate that DTT activity in the southeast US is likely not dominated by a unique local source, and sources change with season. The unique large data set generated with the technique described in this paper allows new studies on DTT sources and investigating linkages between reactive oxygen species and health.