Articles | Volume 9, issue 10
https://doi.org/10.5194/amt-9-4891-2016
© Author(s) 2016. This work is distributed under
the Creative Commons Attribution 3.0 License.
the Creative Commons Attribution 3.0 License.
https://doi.org/10.5194/amt-9-4891-2016
© Author(s) 2016. This work is distributed under
the Creative Commons Attribution 3.0 License.
the Creative Commons Attribution 3.0 License.
Research article
| 
06 Oct 2016
Research article |
| 06 Oct 2016
An automated online instrument to quantify aerosol-bound reactive oxygen species (ROS) for ambient measurement and health-relevant aerosol studies
Francis P. H. Wragg
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2
1EW, UK
Stephen J. Fuller
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2
1EW, UK
Ray Freshwater
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2
1EW, UK
David C. Green
MRC-PHE Centre for Environment and Health, King's College London,
Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, UK
Frank J. Kelly
MRC-PHE Centre for Environment and Health, King's College London,
Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, UK
Markus Kalberer
CORRESPONDING AUTHOR
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2
1EW, UK
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40 citations as recorded by crossref.
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- Diurnal profiles of particle-bound ROS of PM2.5 in urban environment of Hong Kong and their association with PM2.5, black carbon, ozone and PAHs S. Stevanovic et al. 10.1016/j.atmosenv.2019.117023
- Connecting the Oxidative Potential of Secondary Organic Aerosols with Reactive Oxygen Species in Exposed Lung Cells P. Chowdhury et al. 10.1021/acs.est.9b04449
- Development, characterization and first deployment of an improved online reactive oxygen species analyzer J. Zhou et al. 10.5194/amt-11-65-2018
- Evidence of association between aerosol properties and in-vitro cellular oxidative response to PM1, oxidative potential of PM2.5, a biomarker of RNA oxidation, and its dependency on combustion sources F. Costabile et al. 10.1016/j.atmosenv.2019.06.023
- Effect of Atmospheric Aging on Soot Particle Toxicity in Lung Cell Models at the Air–Liquid Interface: Differential Toxicological Impacts of Biogenic and Anthropogenic Secondary Organic Aerosols (SOAs) S. Offer et al. 10.1289/EHP9413
- Application of a Fluorescent Probe for the Online Measurement of PM-Bound Reactive Oxygen Species in Chamber and Ambient Studies R. Brown et al. 10.3390/s19204564
- The oxidative potential of fresh and aged elemental carbon-containing airborne particles: a review Y. Liu & C. Chan 10.1039/D1EM00497B
- Development and Field Testing of an Online Monitoring System for Atmospheric Particle-Bound Reactive Oxygen Species (ROS) Y. Liu et al. 10.3390/atmos14060924
- Relationship between Atmospheric PM-Bound Reactive Oxygen Species, Their Half-Lives, and Regulated Pollutants: Investigation and Preliminary Model R. Brown et al. 10.1021/acs.est.9b06643
- Application of time-of-flight aerosol mass spectrometry for the real-time measurement of particle-phase organic peroxides: an online redox derivatization–aerosol mass spectrometer (ORD-AMS) M. Weloe & T. Hoffmann 10.5194/amt-13-5725-2020
- An instrument for the rapid quantification of PM-bound ROS: the Particle Into Nitroxide Quencher (PINQ) R. Brown et al. 10.5194/amt-12-2387-2019
- Cloud Water Chemistry Associated with Urban Aerosols: Rapid Hydroxyl Radical Formation, Soluble Metals, Fe(II), Fe(III), and Quinones X. Kuang et al. 10.1021/acsearthspacechem.9b00243
- Quantification of Particle-Bound Organic Radicals in Secondary Organic Aerosol S. Campbell et al. 10.1021/acs.est.9b00825
- Characterization of organic compounds and oxidative potential of aqueous PM2.5 suspensions collected via an aerosol-into-liquid collector for use in toxicology studies E. Soleimanian et al. 10.1016/j.atmosenv.2020.117839
- Multiphase composition changes and reactive oxygen species formation during limonene oxidation in the new Cambridge Atmospheric Simulation Chamber (CASC) P. Gallimore et al. 10.5194/acp-17-9853-2017
- Particulate matter (PM) oxidative potential: Measurement methods and links to PM physicochemical characteristics and health effects L. He & J. Zhang 10.1080/10643389.2022.2050148
- Atmospheric conditions and composition that influence PM<sub>2.5</sub> oxidative potential in Beijing, China S. Campbell et al. 10.5194/acp-21-5549-2021
- The diurnal characteristics of PM-bound ROS and its influencing factors at urban ambient and roadside environments N. Gali et al. 10.1016/j.atmosres.2020.105039
- A semi-automated instrument for cellular oxidative potential evaluation (SCOPE) of water-soluble extracts of ambient particulate matter S. Salana et al. 10.5194/amt-14-7579-2021
- Organic Peroxides in Aerosol: Key Reactive Intermediates for Multiphase Processes in the Atmosphere S. Wang et al. 10.1021/acs.chemrev.2c00430
- Development of a Physiologically Relevant Online Chemical Assay To Quantify Aerosol Oxidative Potential S. Campbell et al. 10.1021/acs.analchem.9b03282
- Real-time chemical characterization of atmospheric particulate matter in China: A review Y. Li et al. 10.1016/j.atmosenv.2017.02.027
- Iron and Copper Alter the Oxidative Potential of Secondary Organic Aerosol: Insights from Online Measurements and Model Development S. Campbell et al. 10.1021/acs.est.3c01975
- Recent advances on SOA formation in indoor air, fate and strategies for SOA characterization in indoor air - A review K. Pytel et al. 10.1016/j.scitotenv.2022.156948
- Assessing reactive oxygen and nitrogen species in atmospheric and aquatic environments: Analytical challenges and opportunities E. Simões et al. 10.1016/j.trac.2020.116149
- Emerging technologies for optical spectral detection of reactive oxygen species J. Herman et al. 10.1007/s00216-018-1233-1
- Continuous measurement of reactive oxygen species inside and outside of a residential house during summer A. Eftekhari et al. 10.1111/ina.12789
- Airborne Aerosols and Human Health: Leapfrogging from Mass Concentration to Oxidative Potential C. Molina et al. 10.3390/atmos11090917
- An Overview of the Automated and On-Line Systems to Assess the Oxidative Potential of Particulate Matter A. Carlino et al. 10.3390/atmos14020256
- Development and field testing of an online instrument for measuring the real-time oxidative potential of ambient particulate matter based on dithiothreitol assay J. Puthussery et al. 10.5194/amt-11-5767-2018
- Review of Acellular Assays of Ambient Particulate Matter Oxidative Potential: Methods and Relationships with Composition, Sources, and Health Effects J. Bates et al. 10.1021/acs.est.8b03430
- Atmospheric aging increases the cytotoxicity of bare soot particles in BEAS-2B lung cells M. Pardo et al. 10.1080/02786826.2023.2178878
- Introduction to the special issue “In-depth study of air pollution sources and processes within Beijing and its surrounding region (APHH-Beijing)” Z. Shi et al. 10.5194/acp-19-7519-2019
- Development, characterization, and application of an improved online reactive oxygen species analyzer based on the Monitor for AeRosols and Gases in ambient Air (MARGA) J. Wu et al. 10.5194/amt-15-2623-2022
- Are reactive oxygen species (ROS) a suitable metric to predict toxicity of carbonaceous aerosol particles? Z. Zhang et al. 10.5194/acp-22-1793-2022
- Production of Peroxy Radicals from the Photochemical Reaction of Fatty Acids at the Air–Water Interface N. Hayeck et al. 10.1021/acsearthspacechem.0c00048
- Indoor–Outdoor Oxidative Potential of PM2.5 in Wintertime Fairbanks, Alaska: Impact of Air Infiltration and Indoor Activities Y. Yang et al. 10.1021/acsestair.3c00067
- The oxidation regime and SOA composition in limonene ozonolysis: roles of different double bonds, radicals, and water Y. Gong et al. 10.5194/acp-18-15105-2018
- Exposure to naphthalene and β-pinene-derived secondary organic aerosol induced divergent changes in transcript levels of BEAS-2B cells M. Pardo et al. 10.1016/j.envint.2022.107366
40 citations as recorded by crossref.
- An automated online field instrument to quantify the oxidative potential of aerosol particles via ascorbic acid oxidation B. Utinger et al. 10.5194/amt-16-2641-2023
- Diurnal profiles of particle-bound ROS of PM2.5 in urban environment of Hong Kong and their association with PM2.5, black carbon, ozone and PAHs S. Stevanovic et al. 10.1016/j.atmosenv.2019.117023
- Connecting the Oxidative Potential of Secondary Organic Aerosols with Reactive Oxygen Species in Exposed Lung Cells P. Chowdhury et al. 10.1021/acs.est.9b04449
- Development, characterization and first deployment of an improved online reactive oxygen species analyzer J. Zhou et al. 10.5194/amt-11-65-2018
- Evidence of association between aerosol properties and in-vitro cellular oxidative response to PM1, oxidative potential of PM2.5, a biomarker of RNA oxidation, and its dependency on combustion sources F. Costabile et al. 10.1016/j.atmosenv.2019.06.023
- Effect of Atmospheric Aging on Soot Particle Toxicity in Lung Cell Models at the Air–Liquid Interface: Differential Toxicological Impacts of Biogenic and Anthropogenic Secondary Organic Aerosols (SOAs) S. Offer et al. 10.1289/EHP9413
- Application of a Fluorescent Probe for the Online Measurement of PM-Bound Reactive Oxygen Species in Chamber and Ambient Studies R. Brown et al. 10.3390/s19204564
- The oxidative potential of fresh and aged elemental carbon-containing airborne particles: a review Y. Liu & C. Chan 10.1039/D1EM00497B
- Development and Field Testing of an Online Monitoring System for Atmospheric Particle-Bound Reactive Oxygen Species (ROS) Y. Liu et al. 10.3390/atmos14060924
- Relationship between Atmospheric PM-Bound Reactive Oxygen Species, Their Half-Lives, and Regulated Pollutants: Investigation and Preliminary Model R. Brown et al. 10.1021/acs.est.9b06643
- Application of time-of-flight aerosol mass spectrometry for the real-time measurement of particle-phase organic peroxides: an online redox derivatization–aerosol mass spectrometer (ORD-AMS) M. Weloe & T. Hoffmann 10.5194/amt-13-5725-2020
- An instrument for the rapid quantification of PM-bound ROS: the Particle Into Nitroxide Quencher (PINQ) R. Brown et al. 10.5194/amt-12-2387-2019
- Cloud Water Chemistry Associated with Urban Aerosols: Rapid Hydroxyl Radical Formation, Soluble Metals, Fe(II), Fe(III), and Quinones X. Kuang et al. 10.1021/acsearthspacechem.9b00243
- Quantification of Particle-Bound Organic Radicals in Secondary Organic Aerosol S. Campbell et al. 10.1021/acs.est.9b00825
- Characterization of organic compounds and oxidative potential of aqueous PM2.5 suspensions collected via an aerosol-into-liquid collector for use in toxicology studies E. Soleimanian et al. 10.1016/j.atmosenv.2020.117839
- Multiphase composition changes and reactive oxygen species formation during limonene oxidation in the new Cambridge Atmospheric Simulation Chamber (CASC) P. Gallimore et al. 10.5194/acp-17-9853-2017
- Particulate matter (PM) oxidative potential: Measurement methods and links to PM physicochemical characteristics and health effects L. He & J. Zhang 10.1080/10643389.2022.2050148
- Atmospheric conditions and composition that influence PM<sub>2.5</sub> oxidative potential in Beijing, China S. Campbell et al. 10.5194/acp-21-5549-2021
- The diurnal characteristics of PM-bound ROS and its influencing factors at urban ambient and roadside environments N. Gali et al. 10.1016/j.atmosres.2020.105039
- A semi-automated instrument for cellular oxidative potential evaluation (SCOPE) of water-soluble extracts of ambient particulate matter S. Salana et al. 10.5194/amt-14-7579-2021
- Organic Peroxides in Aerosol: Key Reactive Intermediates for Multiphase Processes in the Atmosphere S. Wang et al. 10.1021/acs.chemrev.2c00430
- Development of a Physiologically Relevant Online Chemical Assay To Quantify Aerosol Oxidative Potential S. Campbell et al. 10.1021/acs.analchem.9b03282
- Real-time chemical characterization of atmospheric particulate matter in China: A review Y. Li et al. 10.1016/j.atmosenv.2017.02.027
- Iron and Copper Alter the Oxidative Potential of Secondary Organic Aerosol: Insights from Online Measurements and Model Development S. Campbell et al. 10.1021/acs.est.3c01975
- Recent advances on SOA formation in indoor air, fate and strategies for SOA characterization in indoor air - A review K. Pytel et al. 10.1016/j.scitotenv.2022.156948
- Assessing reactive oxygen and nitrogen species in atmospheric and aquatic environments: Analytical challenges and opportunities E. Simões et al. 10.1016/j.trac.2020.116149
- Emerging technologies for optical spectral detection of reactive oxygen species J. Herman et al. 10.1007/s00216-018-1233-1
- Continuous measurement of reactive oxygen species inside and outside of a residential house during summer A. Eftekhari et al. 10.1111/ina.12789
- Airborne Aerosols and Human Health: Leapfrogging from Mass Concentration to Oxidative Potential C. Molina et al. 10.3390/atmos11090917
- An Overview of the Automated and On-Line Systems to Assess the Oxidative Potential of Particulate Matter A. Carlino et al. 10.3390/atmos14020256
- Development and field testing of an online instrument for measuring the real-time oxidative potential of ambient particulate matter based on dithiothreitol assay J. Puthussery et al. 10.5194/amt-11-5767-2018
- Review of Acellular Assays of Ambient Particulate Matter Oxidative Potential: Methods and Relationships with Composition, Sources, and Health Effects J. Bates et al. 10.1021/acs.est.8b03430
- Atmospheric aging increases the cytotoxicity of bare soot particles in BEAS-2B lung cells M. Pardo et al. 10.1080/02786826.2023.2178878
- Introduction to the special issue “In-depth study of air pollution sources and processes within Beijing and its surrounding region (APHH-Beijing)” Z. Shi et al. 10.5194/acp-19-7519-2019
- Development, characterization, and application of an improved online reactive oxygen species analyzer based on the Monitor for AeRosols and Gases in ambient Air (MARGA) J. Wu et al. 10.5194/amt-15-2623-2022
- Are reactive oxygen species (ROS) a suitable metric to predict toxicity of carbonaceous aerosol particles? Z. Zhang et al. 10.5194/acp-22-1793-2022
- Production of Peroxy Radicals from the Photochemical Reaction of Fatty Acids at the Air–Water Interface N. Hayeck et al. 10.1021/acsearthspacechem.0c00048
- Indoor–Outdoor Oxidative Potential of PM2.5 in Wintertime Fairbanks, Alaska: Impact of Air Infiltration and Indoor Activities Y. Yang et al. 10.1021/acsestair.3c00067
- The oxidation regime and SOA composition in limonene ozonolysis: roles of different double bonds, radicals, and water Y. Gong et al. 10.5194/acp-18-15105-2018
- Exposure to naphthalene and β-pinene-derived secondary organic aerosol induced divergent changes in transcript levels of BEAS-2B cells M. Pardo et al. 10.1016/j.envint.2022.107366
Latest update: 19 Apr 2024
Short summary
A new portable, online instrument was designed, built and characterised to quantify reactive oxygen species (ROS) in atmospheric aerosols for laboratory and field deployment. ROS are potentially major contributors to the toxicity of particles. Our new instrument allows automated quantification of ROS over days with a detection limit of about 4 nmol [H2O2] equivalents per cubic metre of air, allowing for continuous atmospheric measurements of this important aerosol toxicity parameter.
A new portable, online instrument was designed, built and characterised to quantify reactive...
